It is a rare thing that a date can be a palindrome. But it happens. And the idea is the following, to cover all different date formats and for the given period And to do some useless extraction of the…Read more ›
Exploring pip/tazo PTA for Pseudomonas using popPK simulation. Key finds: 30-min infusions fall short of 90% PTA at MIC 16; prolonged infusion helps, but neutropenic fever population sees the biggest drop in PTA. ~46% of susceptible PsA isolates carry blaOXA-2 — tazobactam matters more than I thought
Motivations
We’ve learnt a bit ...
Required Packages
# install.packages(c("ragnar", "ellmer", "dplyr", "ggplot2", "tibble"))
library(ragnar)
library(ellmer)
library(dplyr)
library(ggplot2)
library(tibble)
Introduction
This earlier post, explored building a text analytics pipe...
Bayesian linear regression is one of the best ways to learn Bayesian modeling in R because it combines familiar regression ideas with a more realistic treatment of uncertainty. Instead of estimating a single fixed coefficient for each parameter, Bayesian methods estimate full probability distributions. That means we can talk about ... [Read more...]
We recently ran a session on Posit platform updates, the kind of features that don’t always make it onto your radar but can make a real difference once you know they’re there.
This post covers the three highlights: speeding up R packa...
This post contains my current views on generative artificial intelligence, and Large Language Models in particular. The context is mostly academia, which is about research and teaching.
Personal context
Generative AI is slowly creeping into my profes... [Read more...]
In honor of Pi Day (March 14), I offer the following:
Does every finite string of numbers like your social security number eventually appear somewhere within the decimal expansion of π ?
&n... [Read more...]
For a while we, at Jumping Rivers, have offered a Dashboard Health Check (DHC) largely focused around backend features and other facets the end-user doesn’t see: things like version control, documentation and deployment. However, the DHC also included a few checks related to user experience and accessibility. While we’...
I’m happy to share a new release of deltatest.
This release includes two main changes:
a new tidy() method for deltatest objects
a fix for p-value calculation in one-sided tests
Before looking at what changed in this release, let’s briefly rev...
The MBBEFD Distribution After two years, the MBBEFDLite package for R is finally mature! As a brand-new actuary, in my first job, I had the privilege of working with Dr. Stefan Bernegger at Swiss Reinsurance. Albeit I did not have much to do with him—I was a one-exam, no ...
You can read the original post in its original format on Rtask website by ThinkR here: Sharing data across shiny modules, an update
Some people have recently been vocal about misuses of the “stratégie du petit r”, a mechanism for sharing data across {shiny} modules that was detailed both ...
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Cluster analysis is a statistical procedure for grouping observations using an observation-centered approach as compared to variable-centered approaches (e.g. PCA, factor analysis). As an unsupervised method true cluster mem... [Read more...]
The patentsview R package was created by Chris Baker to simplify interactions with the
PatentsView API as announced in Chris’
blog post
in 2017. The API can be queried for data from US patents granted since 1976 as well as
patent applications si... [Read more...]
Formula 1 is one of the most compelling areas for data analysis in R because it combines structured results, lap-by-lap timing, pit strategy, and driver performance into one of the richest datasets in sport. For anyone building authority in technical R content, this is an excellent niche: it is specific enough ... [Read more...]
In a previous post, I described how to run a session to teach R to cell biologists. In this post we’ll look in a bit more detail at one of the steps: how to load data into R. As a reminder, a typical analysis task in cell biology follows ... [Read more...]
I’ve spent the last couple of months revising my Data Visualization book for a second edition that, ideally, will appear some time in the next twelve months. As with the first edition, I’ve posted a complete draft of the book at its website...
We are releasing the first version of Leptodon, our Leptos UI toolkit, into the wild.
This release of Leptodon contains UI components for general application development. However, the end goal is to make Leptodon capable enough to easily build comple...
In the last couple of posts (starting here), I’ve tried to unpack some of the ideas that sit underneath TMLE: viewing parameters as functionals of a distribution, thinking about sampling as a perturbation, and understanding how influence functions d... [Read more...]
🧪 Diving into PK/PD for the first time — simulating ceftriaxone with mrgsolve in R. Free drug levels were… surprisingly high? Even pushed it to q48h dosing out of curiosity and the results left me with more questions than answers 🤔📈
Motivations
Learning pharmacokinetics (PK) and pharmocodynamics (PD) have always been ...