Interacting with bioinformatics webservers using R

September 8, 2011 | nsaunders

In an ideal world, all bioinformatics tools would be made available via the Web as a web service with an API, as well as a standalone package to download for local use. This is rarely the case and sometimes, even where one or the other is available, factors such as ... [Read more...]

Popular topics at the BioStar Q&A site

August 23, 2011 | nsaunders

Which topics are the most popular at the BioStar bioinformatics Q&A site? One source of data is the tags used for questions. Tags are somewhat arbitrary of course, but fortunately BioStar has quite an active community, so “bad” tags are usually edited to improve them. Hint: if your question ... [Read more...]

QTL Analysis in R

August 13, 2011 | Matt Bogard

See also: Part 1: QTL Analysis and Quantitative Genetics  Part 2: Statistical Methods for QTL Analysis The 'qtl' package in R allows you to implement QTL analysis using the methods I've previously discussed. The code below is adapted from Broman... [Read more...]

I can’t resist a word cloud: now using R!

July 28, 2011 | nsaunders

The wordcloud package is word clouds for R with a difference: they look great. Of course, having just analysed online coverage of the ISMB conference, I had to run all 6 906 comments from the 2008-2011 meetings through some code. If you followed along via the Sweave code, I went as far ... [Read more...]

Now I’m R-Blogging

July 10, 2011 | Martin Scharm

Today a lot of great mails arrived at my inbox. In one of them I was reading I’ve just added your feed to the site. Where did this mail come from? The sender of the email was Tal Galili. He is a researcher in BioStatistics at the Tel Aviv ... [Read more...]

Mapping SNPs to Genes for GWAS Enrichment Analysis

June 30, 2011 | Will

There are several tools available for conducting a post-hoc analysis of GWAS data looking for enrichment of significant SNPs using literature or pathway based resources. Examples include GRAIL, ALLIGATOR, and WebGestalt among others (see SNPath R Pac...
[Read more...]

R package DOSE released

June 12, 2011 | ygc

Disease Ontology (DO) provides an open source ontology for the integration of biomedical data that is associated with human disease. DO analysis can lead to interesting discoveries that deserve further clinical investigation. DOSE was designed for semantic similarity measure and enrichment analysis. Read More: 619 Words Totally [Read more...]

More Command-Line Text Munging Utilities

May 19, 2011 | Stephen Turner

In a previous post I linked to gcol as a quick and intuitive alternative to awk. I just stumbled across yet another set of handy text file manipulation utilities from the creators of the BEAGLE software for GWAS data imputation and analysis. In additio...
[Read more...]

clusterProfiler in Bioconductor 2.8

March 26, 2011 | R on Guangchuang Yu

In recently years, high-throughput experimental techniques such as microarray and mass spectrometry can identify many lists of genes and gene products. The most widely used strategy for high-throughput data analysis is to identify different gene clusters based on their expression profiles. Another commonly used approach is to annotate these genes ... [Read more...]
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