Articles by Keith Goldfeld

Generating data from a truncated distribution

August 17, 2020 | Keith Goldfeld

A researcher reached out to me the other day to see if the simstudy package provides a quick and easy way to generate data from a truncated distribution. Other than the noZeroPoisson distribution option (which is a very specific truncated distribution), there is no way to do this directly. You ...
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A hurdle model for COVID-19 infections in nursing homes

August 3, 2020 | Keith Goldfeld

Late last year, I added a mixture distribution to the simstudy package, largely motivated to accommodate zero-inflated Poisson or negative binomial distributions. (I really thought I had added this two years ago - but time is moving so slowly these days.) These distributions are useful when modeling count data, but ...
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A Bayesian model for a simulated meta-analysis

July 20, 2020 | Keith Goldfeld

This is essentially an addendum to the previous post where I simulated data from multiple RCTs to explore an analytic method to pool data across different studies. In that post, I used the nlme package to conduct a meta-analysis based on individual level data of 12 studies. Here, I am presenting ...
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Simulating multiple RCTs to simulate a meta-analysis

July 6, 2020 | Keith Goldfeld

I am currently involved with an RCT that is struggling to recruit eligible patients (by no means an unusual problem), increasing the risk that findings might be inconclusive. A possible solution to this conundrum is to find similar, ongoing trials with the aim of pooling data in a single analysis, ...
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