The analysis of variance (ANOVA) model can be extended from making a comparison between multiple groups to take into account additional factors in an experiment. The simplest extension is from one-way to two-way ANOVA where a second factor is included in the model as well as a potential interaction between the two factors. As an example
Zero Inflated Models and Generalized Linear Mixed Models with R.
Zuur, Saveliev, Ieno (2012).
