(This article was first published on Yu-Sung Su's Blog, and kindly contributed to R-bloggers)
This is another example of why defaults matter a lot. I got an email of Evan Cooch forward by Matt, saying that there exists a trick to speed up R matrix caculation. He found that if we replace the default Rblas.dll in R with the proper one. It can boost R's speed in doing matrix caculation. The file is here (This file only works under Windows). For Mac and Linux users, see here. Here are
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Zero Inflated Models and Generalized Linear Mixed Models with R.
Zuur, Saveliev, Ieno (2012).