Over at Cerebral Mastication, JD Long tells a characteristically entertaining and informative story about how he uses R to run stochastic simulations of insurance portfolios and reinsurance treaties. A typical job involves 10,000 simulations, and when each estimate takes over 20 seconds you're talking some serious time to get the job done. Fortunately, this is the kind of problem...

Zero Inflated Models and Generalized Linear Mixed Models with R.
Zuur, Saveliev, Ieno (2012).