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My second-favourite keynote from yesterday's Strata Hadoop World conference was this one, from Pinterest's John Rauser. To many people (especially in the Big Data world), Statistics is a series of complex equations, but a just a little intuition goes a long way to really understanding data. John illustrates this wonderfully using an example of data collected to determine whether consuming beer causes mosquitoes to bite you more:

The big lesson here, IMO, is that so many statistical problems can seem complex, but you can actually get a lot of insight by recognizing that your data is just one possible instance of a random process. If you have a hypothesis for what that process is, you can simulate it, and get an intuitive sense of how surprising your data is. R has excellent tools for simulating data, and a couple of hours spent writing code to simulate data can often give insights that will be valuable for the formal data analysis to come.