ProbABEL – R package for GWAS data imputation

April 6, 2010
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(This article was first published on Getting Genetics Done, and kindly contributed to R-bloggers)

I've been using GenABEL for some time now for GWAS analysis using related individuals. It has an excellent set of functions for estimating a kinship matrix from a dense marker panel and then using this in a linear mixed effects model to allow for related individuals in the analysis of a quantitative trait. GenABEL also has many other nice features for analysis and visualization of GWAS data that

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