Efficient Mixed-Model Association eXpedited (EMMAX) to Simutaneously Account for Relatedness and Stratification in Genome-Wide Association Studies

June 9, 2010

(This article was first published on Getting Genetics Done, and kindly contributed to R-bloggers)

A few months ago I covered an algorithm called EMMA (Efficient Mixed-Model Association) implemented in R for simultaneously correct for both population stratification and relatedness in an association study. This method/software is very useful because most methods that account for relatedness in an association study assume a genetically (ethnically) homogeneous population, while methods that

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