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		<title>Stepping Outside My Open-Source Comfort Zone: A First Look at Golden Helix SVS</title>
		<link>http://www.r-bloggers.com/stepping-outside-my-open-source-comfort-zone-a-first-look-at-golden-helix-svs/</link>
		<comments>http://www.r-bloggers.com/stepping-outside-my-open-source-comfort-zone-a-first-look-at-golden-helix-svs/#comments</comments>
		<pubDate>Wed, 16 May 2012 16:29:00 +0000</pubDate>
		<dc:creator>Stephen Turner</dc:creator>
				<category><![CDATA[R bloggers]]></category>
		<category><![CDATA[Bioinformatics]]></category>
		<category><![CDATA[PLINK]]></category>
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		<guid isPermaLink="false">http://www.r-bloggers.com/?guid=648d274da4b4e80c13991dae57d242b6</guid>
		<description><![CDATA[I'm a huge supporter of the Free and Open Source Software movement. I've written more about R than anything else on this blog, all the code I post here is free and open-source, and a while back I invited you to steal this blog under a cc-by-sa license....]]></description>
			<content:encoded><![CDATA[<p class="syndicated-attribution"><div style="border: 1px solid; background: none repeat scroll 0 0 #EDEDED; margin: 1px; font-size: 12px;">
(This article was first published on  <strong><a href="http://gettinggeneticsdone.blogspot.com/2012/05/stepping-outside-my-open-source-comfort.html"> Getting Genetics Done</a></strong>, and kindly contributed to <a href="http://www.r-bloggers.com/">R-bloggers)</a>      
</div></p>
I'm a huge supporter of the Free and Open Source Software movement. I've <a href="http://gettinggeneticsdone.blogspot.com/search/label/R" ref="nofollow" target="_blank">written more about R</a> than anything else on this blog, all the code I post here <a href="http://gettinggeneticsdone.blogspot.com/p/license.html" ref="nofollow" target="_blank">is free and open-source</a>, and a while back I invited you to <a href="http://gettinggeneticsdone.blogspot.com/2011/06/steal-this-blog.html" ref="nofollow" target="_blank">steal this blog</a> under a cc-by-sa license.<br /><br />Every now and then, however, something comes along that just might be worth paying for. As a director of a bioinformatics core with a very small staff, I spend a lot of time balancing costs like software licensing versus personnel/development time, so that I can continue to provide a fiscally sustainable high-quality service.<br /><br />As you've likely noticed from my more recent blog/twitter posts, the core has been doing a lot of gene expression and RNA-seq work. But recently had a client who wanted to run a fairly standard case-control GWAS analysis on a dataset from dbGaP. Since this isn't the focus of my core's service, I didn't want to invest the personnel time in deploying a GWAS analysis pipeline, downloading and compiling all the tools I would normally use if I were doing this routinely, and spending hours on forums trying to remember what to do with procedural issues such as which options to specify when running <a href="http://genepath.med.harvard.edu/~reich/EIGENSTRAT.htm" ref="nofollow" target="_blank">EIGENSTRAT</a>&nbsp;or&nbsp;<a href="http://people.virginia.edu/~wc9c/KING/index.html" ref="nofollow" target="_blank">KING</a>, or trying to remember how to subset and LD-prune a binary PED file, or scientific issues, such as whether GWAS data should be LD-pruned at all before doing PCA.<br /><br /><b>Golden Helix</b><br /><br />A year ago I <a href="http://gettinggeneticsdone.blogspot.com/2011/05/golden-helix-hitchhikers-guide-to-next.html" ref="nofollow" target="_blank">wrote a post</a> about the "<a href="http://www.goldenhelix.com/pdfs/Hitchhikers-Guide-to-NGS.pdf" ref="nofollow" target="_blank">Hitchhiker's Guide to Next-Gen Sequencing</a>" by Gabe Rudy, a scientist at <a href="http://goldenhelix.com/" ref="nofollow" target="_blank">Golden Helix</a>. After reading this and looking through other posts on their <a href="http://blog.goldenhelix.com/" ref="nofollow" target="_blank">blog</a>, I'm confident that these guys know what they're doing and it would be worth giving their product a try.&nbsp;Luckily, I had the opportunity to try out their&nbsp;<a href="http://goldenhelix.com/SNP_Variation/index.html" ref="nofollow" target="_blank">SNP &amp; Variation Suite</a> (SVS)&nbsp;software (I believe you can also get a free trial on their website).<br /><br />I'm not going to talk about the software - that's for a future post if the core continues to get any more GWAS analysis projects. In summary - it was fairly painless to learn a new interface, import the data, do some basic QA/QC, run a PCA-adjusted logistic regression, and produce some nice visualization. What I want to highlight here is the level of support and documentation you get with SVS.<br /><br /><b>Documentation</b><br /><br />First, the documentation.&nbsp;At each step from data import through analysis and visualization there's a help button that opens up the manual at the page you need. This contextual manual not only gives operational details about where you click or which options to check, but also gives scientific explanations of why you might use certain procedures in certain scenarios. Here's a small excerpt of the context-specific help menu that appeared when I asked for help doing PCA.<br /><br /><div class="separator" style="clear: both; text-align: center;"><a href="http://2.bp.blogspot.com/-FCcYR5hPEN8/T6lOda5uhvI/AAAAAAAAsH4/BNawObDgL3I/s1600/Screen+Shot+2012-05-08+at+12.45.14+PM.png" imageanchor="1" style="margin-left: 1em; margin-right: 1em;" ref="nofollow" target="_blank"><img border="0" height="640" src="http://2.bp.blogspot.com/-FCcYR5hPEN8/T6lOda5uhvI/AAAAAAAAsH4/BNawObDgL3I/s640/Screen+Shot+2012-05-08+at+12.45.14+PM.png" width="609" /></a></div>What I really want to draw your attention to here is that even if you don't use SVS you can still view their <a href="http://doc.goldenhelix.com/SVS/latest/" ref="nofollow" target="_blank">manual</a> online without registering, giving them your e-mail, or downloading any trialware. Think of this manual as an always up-to-date mega-review of GWAS - with it you can learn quite a bit about GWAS analysis, quality control, and statistics. For example, see this section on <a href="http://doc.goldenhelix.com/SVS/latest/formulas_theories.html#haplotype-frequency-estimation-methods" ref="nofollow" target="_blank">haplotype frequency estimation and the EM algorithm</a>. The section on the mathematical motivation and implementation of the Eigenstrat PCA method explains the method perhaps better than the Eigenstrat paper and documentation itself. There are also lots of <a href="http://www.goldenhelix.com/SNP_Variation/tutorials/index.html" ref="nofollow" target="_blank">video tutorials</a> that are helpful, even if you're not using SVS. This is a great resource, whether you're just trying to get a better grip on what PLINK is doing, or perhaps implementing some of these methods in your own software.<br /><br /><b>Support</b><br /><br />Next, the support. After installing SVS on both my Mac laptop and the Linux box where I do my heavy lifting, one of the product specialists at Golden Helix <i>called</i> me and walked me through every step of a GWAS analysis, from QC to analysis to visualization. While analyzing the dbGaP data for my client I ran into both software-specific procedural issues as well as general scientific questions.&nbsp;If you've ever asked a basic question on the R-help mailing list, you know need some patience and a thick skin for all the RTFM responses you'll get. I was able to call the fine folks at Golden Helix and get both my technical and scientific questions answered in the same day. There are <a href="http://gettinggeneticsdone.blogspot.com/2011/02/get-all-your-questions-answered.html" ref="nofollow" target="_blank">lots of resources for getting your questions answered</a>, such as <a href="http://seqanswers.com/" ref="nofollow" target="_blank">SEQanswers</a>, <a href="http://biostars.org/" ref="nofollow" target="_blank">Biostar</a>, <a href="http://stats.stackexchange.com/" ref="nofollow" target="_blank">Cross Validated</a>, and <a href="http://stackoverflow.com/" ref="nofollow" target="_blank">StackOverflow</a> to name a few, but getting a forum response two days later from "SeqGeek96815" doesn't compare to having a team of scientists, statisticians, programmers, and product specialists on the other end of a <i>telephone</i>&nbsp;whose job it is to answer your questions.<br /><br /><b>Final Thoughts</b><br /><br />This isn't meant to be a wholesale endorsement of Golden Helix or any other particular software company - I only wanted to share my experience stepping outside my comfortable open-source world into the walled garden of a commercially-licensed software from a for-profit company (the walls on the SVS garden aren't that high in reality - you can import and export data in any format imaginable). One of the nice things about command-line based tools is that it's relatively easy to automate a simple (or at least well-documented) process with tools like Galaxy, Taverna, or even by wrapping them with perl or bash scripts. However, the types of data my clients are collecting and the kinds of questions they're asking are always a little new and different, which means I'm rarely doing the same exact analysis twice. Because of the level of documentation and support provided to me, I was able to learn a new interface to a set of familiar procedures and run an analysis very quickly and without spending hours on forums figuring out why a particular program is seg-faulting. Will I abandon open-source tools like PLINK for SVS, Tophat-Cufflinks for CLC Workbench, BWA for NovoAlign, or R for Stata? Not in a million years. I haven't talked to Golden Helix or some of the above-mentioned companies about pricing for their products, but if I can spend a few bucks and save the time it would taken a full time technician at $50k+/year to write a new short read aligner or build a new SNP annotation database server, then I'll be able to provide a faster, high-quality, fiscally sustainable service at a much lower price for the core's clients, which is all-important in a time when federal funding is increasingly harder to come by.<div class="blogger-post-footer">Getting Genetics Done by Stephen Turner is licensed under a Creative Commons Attribution-ShareAlike 3.0 Unported License.<img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/6232819486261696035-2518421525750074300?l=gettinggeneticsdone.blogspot.com' alt='' /></div>
<p class="syndicated-attribution"><div style="border: 1px solid; background: none repeat scroll 0 0 #EDEDED; margin: 1px; font-size: 13px;">
<div style="text-align: center;">To <strong>leave a comment</strong> for the author, please follow the link and comment on his blog: <strong><a href="http://gettinggeneticsdone.blogspot.com/2012/05/stepping-outside-my-open-source-comfort.html"> Getting Genetics Done</a></strong>.</div>
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		</item>
		<item>
		<title>Population of Tawi-Tawi from 1903 to 2010</title>
		<link>http://www.r-bloggers.com/population-of-tawi-tawi-from-1903-to-2010/</link>
		<comments>http://www.r-bloggers.com/population-of-tawi-tawi-from-1903-to-2010/#comments</comments>
		<pubDate>Wed, 16 May 2012 08:17:00 +0000</pubDate>
		<dc:creator>alstated</dc:creator>
				<category><![CDATA[R bloggers]]></category>
		<category><![CDATA[Population]]></category>
		<category><![CDATA[R]]></category>
		<category><![CDATA[R Programming]]></category>
		<category><![CDATA[Tawi-Tawi Population]]></category>

		<guid isPermaLink="false">http://www.r-bloggers.com/?guid=8b19c8186f0ec212b1082a6a4a2c9216</guid>
		<description><![CDATA[   Table   1: Population of Tawi-Tawi from 1903 to 2010   1903  1918  1939  1948  1960  1970  1975  1980  1990  1995  2000  2007  2010   17000  45000  46000  59000  79000  110000  143000  195000  228204  250718  322317  450346  366550    R Codes]]></description>
			<content:encoded><![CDATA[<p class="syndicated-attribution"><div style="border: 1px solid; background: none repeat scroll 0 0 #EDEDED; margin: 1px; font-size: 12px;">
(This article was first published on  <strong><a href="http://alstatr.blogspot.com/2012/05/population-of-tawi-tawi-from-1903-to.html"> ALSTAT R Blog</a></strong>, and kindly contributed to <a href="http://www.r-bloggers.com/">R-bloggers)</a>      
</div></p>
<div align="center"><br /><table border="1" cellpadding="0" cellspacing="0" class="MsoTableGrid" style="border-bottom-style: none; border-collapse: collapse; border-color: initial; border-image: initial; border-left-style: none; border-right-style: none; border-top-style: none; border-width: initial; margin-left: -39.75pt; width: 478px;"> <tbody><tr style="height: 17.05pt; mso-yfti-firstrow: yes; mso-yfti-irow: 0;">  <td colspan="13" style="border: solid windowtext 1.0pt; height: 17.05pt; mso-border-alt: solid windowtext .5pt; padding: 0in 5.4pt 0in 5.4pt; width: 358.5pt;" width="478"><div align="center" class="MsoNormal" style="margin-bottom: 0.0001pt; text-align: center;"><b><span style="font-family: 'Century Gothic', sans-serif; font-size: 8pt;">Table   1: Population of Tawi-Tawi from 1903 to 2010<o:p></o:p></span></b></div></td> </tr><tr style="height: 27.55pt; mso-yfti-irow: 1;">  <td style="border-top: none; border: solid windowtext 1.0pt; height: 27.55pt; mso-border-alt: solid windowtext .5pt; mso-border-top-alt: solid windowtext .5pt; padding: 0in 5.4pt 0in 5.4pt; width: 25.55pt;" width="34"><div align="center" class="MsoNormal" style="margin-bottom: 0.0001pt; text-align: center;"><i><span style="font-size: 8pt;">1903<o:p></o:p></span></i></div></td>  <td style="border-bottom: solid windowtext 1.0pt; border-left: none; border-right: solid windowtext 1.0pt; border-top: none; height: 27.55pt; mso-border-alt: solid windowtext .5pt; mso-border-left-alt: solid windowtext .5pt; mso-border-top-alt: solid windowtext .5pt; padding: 0in 5.4pt 0in 5.4pt; width: 25.55pt;" width="34"><div align="center" class="MsoNormal" style="margin-bottom: 0.0001pt; text-align: center;"><i><span style="font-size: 8pt;">1918<o:p></o:p></span></i></div></td>  <td style="border-bottom: solid windowtext 1.0pt; border-left: none; border-right: solid windowtext 1.0pt; border-top: none; height: 27.55pt; mso-border-alt: solid windowtext .5pt; mso-border-left-alt: solid windowtext .5pt; mso-border-top-alt: solid windowtext .5pt; padding: 0in 5.4pt 0in 5.4pt; width: 25.55pt;" width="34"><div align="center" class="MsoNormal" style="margin-bottom: 0.0001pt; text-align: center;"><i><span style="font-size: 8pt;">1939<o:p></o:p></span></i></div></td>  <td style="border-bottom: solid windowtext 1.0pt; border-left: none; border-right: solid windowtext 1.0pt; border-top: none; height: 27.55pt; mso-border-alt: solid windowtext .5pt; mso-border-left-alt: solid windowtext .5pt; mso-border-top-alt: solid windowtext .5pt; padding: 0in 5.4pt 0in 5.4pt; width: 25.55pt;" width="34"><div align="center" class="MsoNormal" style="margin-bottom: 0.0001pt; text-align: center;"><i><span style="font-size: 8pt;">1948<o:p></o:p></span></i></div></td>  <td style="border-bottom: solid windowtext 1.0pt; border-left: none; border-right: solid windowtext 1.0pt; border-top: none; height: 27.55pt; mso-border-alt: solid windowtext .5pt; mso-border-left-alt: solid windowtext .5pt; mso-border-top-alt: solid windowtext .5pt; padding: 0in 5.4pt 0in 5.4pt; width: 25.55pt;" width="34"><div align="center" class="MsoNormal" style="margin-bottom: 0.0001pt; text-align: center;"><i><span style="font-size: 8pt;">1960<o:p></o:p></span></i></div></td>  <td style="border-bottom: solid windowtext 1.0pt; border-left: none; border-right: solid windowtext 1.0pt; border-top: none; height: 27.55pt; mso-border-alt: solid windowtext .5pt; mso-border-left-alt: solid windowtext .5pt; mso-border-top-alt: solid windowtext .5pt; padding: 0in 5.4pt 0in 5.4pt; width: 28.85pt;" width="38"><div align="center" class="MsoNormal" style="margin-bottom: 0.0001pt; text-align: center;"><i><span style="font-size: 8pt;">1970<o:p></o:p></span></i></div></td>  <td style="border-bottom: solid windowtext 1.0pt; border-left: none; border-right: solid windowtext 1.0pt; border-top: none; height: 27.55pt; mso-border-alt: solid windowtext .5pt; mso-border-left-alt: solid windowtext .5pt; mso-border-top-alt: solid windowtext .5pt; padding: 0in 5.4pt 0in 5.4pt; width: 28.85pt;" width="38"><div align="center" class="MsoNormal" style="margin-bottom: 0.0001pt; text-align: center;"><i><span style="font-size: 8pt;">1975<o:p></o:p></span></i></div></td>  <td style="border-bottom: solid windowtext 1.0pt; border-left: none; border-right: solid windowtext 1.0pt; border-top: none; height: 27.55pt; mso-border-alt: solid windowtext .5pt; mso-border-left-alt: solid windowtext .5pt; mso-border-top-alt: solid windowtext .5pt; padding: 0in 5.4pt 0in 5.4pt; width: 28.85pt;" width="38"><div align="center" class="MsoNormal" style="margin-bottom: 0.0001pt; text-align: center;"><i><span style="font-size: 8pt;">1980<o:p></o:p></span></i></div></td>  <td style="border-bottom: solid windowtext 1.0pt; border-left: none; border-right: solid windowtext 1.0pt; border-top: none; height: 27.55pt; mso-border-alt: solid windowtext .5pt; mso-border-left-alt: solid windowtext .5pt; mso-border-top-alt: solid windowtext .5pt; padding: 0in 5.4pt 0in 5.4pt; width: 28.85pt;" width="38"><div align="center" class="MsoNormal" style="margin-bottom: 0.0001pt; text-align: center;"><i><span style="font-size: 8pt;">1990<o:p></o:p></span></i></div></td>  <td style="border-bottom: solid windowtext 1.0pt; border-left: none; border-right: solid windowtext 1.0pt; border-top: none; height: 27.55pt; mso-border-alt: solid windowtext .5pt; mso-border-left-alt: solid windowtext .5pt; mso-border-top-alt: solid windowtext .5pt; padding: 0in 5.4pt 0in 5.4pt; width: 28.85pt;" width="38"><div align="center" class="MsoNormal" style="margin-bottom: 0.0001pt; text-align: center;"><i><span style="font-size: 8pt;">1995<o:p></o:p></span></i></div></td>  <td style="border-bottom: solid windowtext 1.0pt; border-left: none; border-right: solid windowtext 1.0pt; border-top: none; height: 27.55pt; mso-border-alt: solid windowtext .5pt; mso-border-left-alt: solid windowtext .5pt; mso-border-top-alt: solid windowtext .5pt; padding: 0in 5.4pt 0in 5.4pt; width: 28.85pt;" width="38"><div align="center" class="MsoNormal" style="margin-bottom: 0.0001pt; text-align: center;"><i><span style="font-size: 8pt;">2000<o:p></o:p></span></i></div></td>  <td style="border-bottom: solid windowtext 1.0pt; border-left: none; border-right: solid windowtext 1.0pt; border-top: none; height: 27.55pt; mso-border-alt: solid windowtext .5pt; mso-border-left-alt: solid windowtext .5pt; mso-border-top-alt: solid windowtext .5pt; padding: 0in 5.4pt 0in 5.4pt; width: 28.85pt;" width="38"><div align="center" class="MsoNormal" style="margin-bottom: 0.0001pt; text-align: center;"><i><span style="font-size: 8pt;">2007<o:p></o:p></span></i></div></td>  <td style="border-bottom: solid windowtext 1.0pt; border-left: none; border-right: solid windowtext 1.0pt; border-top: none; height: 27.55pt; mso-border-alt: solid windowtext .5pt; mso-border-left-alt: solid windowtext .5pt; mso-border-top-alt: solid windowtext .5pt; padding: 0in 5.4pt 0in 5.4pt; width: 28.85pt;" width="38"><div align="center" class="MsoNormal" style="margin-bottom: 0.0001pt; text-align: center;"><i><span style="font-size: 8pt;">2010<o:p></o:p></span></i></div></td> </tr><tr style="height: 28.75pt; mso-yfti-irow: 2; mso-yfti-lastrow: yes;">  <td style="border-top: none; border: solid windowtext 1.0pt; height: 28.75pt; mso-border-alt: solid windowtext .5pt; mso-border-top-alt: solid windowtext .5pt; padding: 0in 5.4pt 0in 5.4pt; width: 25.55pt;" width="34"><div align="center" class="MsoNormal" style="margin-bottom: 0.0001pt; text-align: center;"><b><span style="font-size: 8pt;">17000<o:p></o:p></span></b></div></td>  <td style="border-bottom: solid windowtext 1.0pt; border-left: none; border-right: solid windowtext 1.0pt; border-top: none; height: 28.75pt; mso-border-alt: solid windowtext .5pt; mso-border-left-alt: solid windowtext .5pt; mso-border-top-alt: solid windowtext .5pt; padding: 0in 5.4pt 0in 5.4pt; width: 25.55pt;" width="34"><div align="center" class="MsoNormal" style="margin-bottom: 0.0001pt; text-align: center;"><b><span style="font-size: 8pt;">45000<o:p></o:p></span></b></div></td>  <td style="border-bottom: solid windowtext 1.0pt; border-left: none; border-right: solid windowtext 1.0pt; border-top: none; height: 28.75pt; mso-border-alt: solid windowtext .5pt; mso-border-left-alt: solid windowtext .5pt; mso-border-top-alt: solid windowtext .5pt; padding: 0in 5.4pt 0in 5.4pt; width: 25.55pt;" width="34"><div align="center" class="MsoNormal" style="margin-bottom: 0.0001pt; text-align: center;"><b><span style="font-size: 8pt;">46000<o:p></o:p></span></b></div></td>  <td style="border-bottom: solid windowtext 1.0pt; border-left: none; border-right: solid windowtext 1.0pt; border-top: none; height: 28.75pt; mso-border-alt: solid windowtext .5pt; mso-border-left-alt: solid windowtext .5pt; mso-border-top-alt: solid windowtext .5pt; padding: 0in 5.4pt 0in 5.4pt; width: 25.55pt;" width="34"><div align="center" class="MsoNormal" style="margin-bottom: 0.0001pt; text-align: center;"><b><span style="font-size: 8pt;">59000<o:p></o:p></span></b></div></td>  <td style="border-bottom: solid windowtext 1.0pt; border-left: none; border-right: solid windowtext 1.0pt; border-top: none; height: 28.75pt; mso-border-alt: solid windowtext .5pt; mso-border-left-alt: solid windowtext .5pt; mso-border-top-alt: solid windowtext .5pt; padding: 0in 5.4pt 0in 5.4pt; width: 25.55pt;" width="34"><div align="center" class="MsoNormal" style="margin-bottom: 0.0001pt; text-align: center;"><b><span style="font-size: 8pt;">79000<o:p></o:p></span></b></div></td>  <td style="border-bottom: solid windowtext 1.0pt; border-left: none; border-right: solid windowtext 1.0pt; border-top: none; height: 28.75pt; mso-border-alt: solid windowtext .5pt; mso-border-left-alt: solid windowtext .5pt; mso-border-top-alt: solid windowtext .5pt; padding: 0in 5.4pt 0in 5.4pt; width: 28.85pt;" width="38"><div align="center" class="MsoNormal" style="margin-bottom: 0.0001pt; text-align: center;"><b><span style="font-size: 8pt;">110000<o:p></o:p></span></b></div></td>  <td style="border-bottom: solid windowtext 1.0pt; border-left: none; border-right: solid windowtext 1.0pt; border-top: none; height: 28.75pt; mso-border-alt: solid windowtext .5pt; mso-border-left-alt: solid windowtext .5pt; mso-border-top-alt: solid windowtext .5pt; padding: 0in 5.4pt 0in 5.4pt; width: 28.85pt;" width="38"><div align="center" class="MsoNormal" style="margin-bottom: 0.0001pt; text-align: center;"><b><span style="font-size: 8pt;">143000<o:p></o:p></span></b></div></td>  <td style="border-bottom: solid windowtext 1.0pt; border-left: none; border-right: solid windowtext 1.0pt; border-top: none; height: 28.75pt; mso-border-alt: solid windowtext .5pt; mso-border-left-alt: solid windowtext .5pt; mso-border-top-alt: solid windowtext .5pt; padding: 0in 5.4pt 0in 5.4pt; width: 28.85pt;" width="38"><div align="center" class="MsoNormal" style="margin-bottom: 0.0001pt; text-align: center;"><b><span style="font-size: 8pt;">195000<o:p></o:p></span></b></div></td>  <td style="border-bottom: solid windowtext 1.0pt; border-left: none; border-right: solid windowtext 1.0pt; border-top: none; height: 28.75pt; mso-border-alt: solid windowtext .5pt; mso-border-left-alt: solid windowtext .5pt; mso-border-top-alt: solid windowtext .5pt; padding: 0in 5.4pt 0in 5.4pt; width: 28.85pt;" width="38"><div align="center" class="MsoNormal" style="margin-bottom: 0.0001pt; text-align: center;"><b><span style="font-size: 8pt;">228204<o:p></o:p></span></b></div></td>  <td style="border-bottom: solid windowtext 1.0pt; border-left: none; border-right: solid windowtext 1.0pt; border-top: none; height: 28.75pt; mso-border-alt: solid windowtext .5pt; mso-border-left-alt: solid windowtext .5pt; mso-border-top-alt: solid windowtext .5pt; padding: 0in 5.4pt 0in 5.4pt; width: 28.85pt;" width="38"><div align="center" class="MsoNormal" style="margin-bottom: 0.0001pt; text-align: center;"><b><span style="font-size: 8pt;">250718<o:p></o:p></span></b></div></td>  <td style="border-bottom: solid windowtext 1.0pt; border-left: none; border-right: solid windowtext 1.0pt; border-top: none; height: 28.75pt; mso-border-alt: solid windowtext .5pt; mso-border-left-alt: solid windowtext .5pt; mso-border-top-alt: solid windowtext .5pt; padding: 0in 5.4pt 0in 5.4pt; width: 28.85pt;" width="38"><div align="center" class="MsoNormal" style="margin-bottom: 0.0001pt; text-align: center;"><b><span style="font-size: 8pt;">322317<o:p></o:p></span></b></div></td>  <td style="border-bottom: solid windowtext 1.0pt; border-left: none; border-right: solid windowtext 1.0pt; border-top: none; height: 28.75pt; mso-border-alt: solid windowtext .5pt; mso-border-left-alt: solid windowtext .5pt; mso-border-top-alt: solid windowtext .5pt; padding: 0in 5.4pt 0in 5.4pt; width: 28.85pt;" width="38"><div align="center" class="MsoNormal" style="margin-bottom: 0.0001pt; text-align: center;"><b><span style="font-size: 8pt;">450346<o:p></o:p></span></b></div></td>  <td style="border-bottom: solid windowtext 1.0pt; border-left: none; border-right: solid windowtext 1.0pt; border-top: none; height: 28.75pt; mso-border-alt: solid windowtext .5pt; mso-border-left-alt: solid windowtext .5pt; mso-border-top-alt: solid windowtext .5pt; padding: 0in 5.4pt 0in 5.4pt; width: 28.85pt;" width="38"><div align="center" class="MsoNormal" style="margin-bottom: 0.0001pt; text-align: center;"><b><span style="font-size: 8pt;">366550<o:p></o:p></span></b></div></td> </tr></tbody></table></div><br /><div class="separator" style="clear: both; text-align: center;"></div><div class="separator" style="clear: both; text-align: center;"></div><div class="separator" style="clear: both; text-align: center;"><a href="http://4.bp.blogspot.com/-aCIFR94-HV0/T7NhotvxAkI/AAAAAAAAASY/jzth2oT1ol0/s1600/Rplot06.png" imageanchor="1" style="clear: left; float: left; margin-bottom: 1em; margin-right: 1em;" ref="nofollow" target="_blank"><img border="0" src="http://4.bp.blogspot.com/-aCIFR94-HV0/T7NhotvxAkI/AAAAAAAAASY/jzth2oT1ol0/s1600/Rplot06.png" /></a></div><br /><div class="separator" style="clear: both; text-align: left;"></div><h3>   R Codes</h3><div><br /></div><script src="https://gist.github.com/2706708.js?file=Tawi-Tawi%20Population.r"></script><div class="blogger-post-footer"><img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/5374984225619933578-1244833942154001066?l=alstatr.blogspot.com' alt='' /></div>
<p class="syndicated-attribution"><div style="border: 1px solid; background: none repeat scroll 0 0 #EDEDED; margin: 1px; font-size: 13px;">
<div style="text-align: center;">To <strong>leave a comment</strong> for the author, please follow the link and comment on his blog: <strong><a href="http://alstatr.blogspot.com/2012/05/population-of-tawi-tawi-from-1903-to.html"> ALSTAT R Blog</a></strong>.</div>
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<a href="http://www.r-bloggers.com/">R-bloggers.com</a> offers <strong><a href="http://feedburner.google.com/fb/a/mailverify?uri=RBloggers">daily e-mail updates</a></strong> about <a title="The R Project for Statistical Computing" href="http://www.r-project.org/">R</a> news and <a title="R tutorials" href="http://www.r-bloggers.com/?s=tutorial">tutorials</a> on topics such as: visualization (<a title="ggplot and ggplot2 tutorials" href="http://www.r-bloggers.com/?s=ggplot2">ggplot2</a>, <a title="Boxplots using lattice and ggplot2 tutorials" href="http://www.r-bloggers.com/?s=boxplot">Boxplots</a>, <a title="Maps and gis" href="http://www.r-bloggers.com/?s=map">maps</a>, <a title="Animation in R" href="http://www.r-bloggers.com/?s=animation">animation</a>), programming (<a title="RStudio IDE for R" href="http://www.r-bloggers.com/?s=RStudio">RStudio</a>, <a title="Sweave and literate programming" href="http://www.r-bloggers.com/?s=sweave">Sweave</a>, <a title="LaTeX in R" href="http://www.r-bloggers.com/?s=LaTeX">LaTeX</a>, <a title="SQL and databases" href="http://www.r-bloggers.com/?s=SQL">SQL</a>, <a title="Eclipse IDE for R" href="http://www.r-bloggers.com/?s=eclipse">Eclipse</a>, <a title="git and github, Version Control System" href="http://www.r-bloggers.com/?s=git">git</a>, <a title="Large data in R using Hadoop" href="http://www.r-bloggers.com/?s=hadoop">hadoop</a>, <a title="Web Scraping of google, facebook, yahoo, twitter and more using R" href="http://www.r-bloggers.com/?s=Web+Scraping">Web Scraping</a>) statistics (<a title="Regressions and ANOVA analysis tutorials" href="http://www.r-bloggers.com/?s=regression">regression</a>, <a title="principal component analysis tutorial" href="http://www.r-bloggers.com/?s=PCA">PCA</a>, <a title="Time series" href="http://www.r-bloggers.com/?s=time+series">time series</a>,<a title="ecdf" href="http://www.r-bloggers.com/?s=ecdf">ecdf</a>, <a title="finance trading" href="http://www.r-bloggers.com/?s=trading">trading</a>) and more...
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		<title>Dynamic Content with RStudio, Markdown, and Marked.</title>
		<link>http://www.r-bloggers.com/dynamic-content-with-rstudio-markdown-and-marked/</link>
		<comments>http://www.r-bloggers.com/dynamic-content-with-rstudio-markdown-and-marked/#comments</comments>
		<pubDate>Wed, 16 May 2012 00:17:00 +0000</pubDate>
		<dc:creator>Christopher Gandrud</dc:creator>
				<category><![CDATA[R bloggers]]></category>
		<category><![CDATA[data analysis teaching]]></category>
		<category><![CDATA[r-project]]></category>
		<category><![CDATA[reproducibility]]></category>

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		<description><![CDATA[As Markus Gesmann recently pointed out, the new version of RStudio (0.96) has some really nice features for creating dynamic reports with Yihui Xie&#8217;s knitr. You can integrate not just R and LaTeX, but also R and Markdown (as well as some other fo...]]></description>
			<content:encoded><![CDATA[<p class="syndicated-attribution"><div style="border: 1px solid; background: none repeat scroll 0 0 #EDEDED; margin: 1px; font-size: 12px;">
(This article was first published on  <strong><a href="http://christophergandrud.blogspot.com/2012/05/dynamic-content-with-rstudio-markdown.html"> Christopher Gandrud</a></strong>, and kindly contributed to <a href="http://www.r-bloggers.com/">R-bloggers)</a>      
</div></p>
<p>As Markus Gesmann recently <a href="http://lamages.blogspot.com/2012/05/interactive-reports-in-r-with-knitr-and.html" ref="nofollow" target="_blank">pointed out</a>, the new version of <a href="http://rstudio.org/" ref="nofollow" target="_blank">RStudio</a> (0.96) has some really nice features for creating dynamic reports with <a href="http://yihui.name/" ref="nofollow" target="_blank">Yihui Xie</a>&#8217;s <a href="http://yihui.name/knitr/" ref="nofollow" target="_blank">knitr</a>. You can integrate not just <strong>R</strong> and <span class="math">LaTeX</span>, but also <strong>R</strong> and <a href="http://daringfireball.net/projects/markdown/" ref="nofollow" target="_blank">Markdown</a> (as well as some other formats). </p> <p>If you haven&#8217;t used Markdown before, it&#8217;s basically a really simplified syntax for writing web content, though it can easily be converted not just to HTML but also <span class="math">LaTeX</span> and other formats with <a href="http://johnmacfarlane.net/pandoc/" ref="nofollow" target="_blank">Pandoc</a>.</p> <p>See this <a href="http://yihui.name/en/2012/05/how-to-make-html5-slides-with-knitr/" ref="nofollow" target="_blank">post</a> by Yihui Xie for a discussion of how to make HTML presentations with knitr and Pandoc. These programs make it much easier to create HTML presentations that display interactive <strong>R</strong> output from packages like <a href="http://cran.r-project.org/web/packages/googleVis/index.html" ref="nofollow" target="_blank">googleVis</a> (like I did in an earlier <a href="http://christophergandrud.blogspot.com/2011/10/world-bank-visualizations-with.html" ref="nofollow" target="_blank">post</a>).</p> <p>I&#8217;ve been using <strong>RStudio</strong>&#8217;s new features in the preview version for a few weeks and it has been really great. It has made creating web content much easier. I&#8217;ve even decided to pretty much move my entire <a href="https://github.com/christophergandrud/Introduction_to_Statistics_and_Data_Analysis_Yonsei/blob/master/README.md" ref="nofollow" target="_blank">introductory data analysis course</a> to the web because I can create lecture notes and assignments with nice syntax highlighting and <strong>R</strong> output integration (especially interactive output).</p> <p>I remember a few years ago saying to my PhD supervisor that I thought it would someday be standard for theses to be written in HTML. Maybe I need to revise that slightly: theses may be displayed in HTML, but written in Markdown or (more specifically) <a href="http://fletcherpenney.net/multimarkdown/" ref="nofollow" target="_blank">MultiMarkdown</a> (which has footnote and BibTeX integration).</p> <h2 id="recommendation">Recommendation</h2> <p>A small program I really recommend purchasing if you are using <strong>RStudio</strong> with Markdown is <a href="http://markedapp.com/" ref="nofollow" target="_blank">Marked</a>. <strong>RStudio</strong> has a Markdown previewer, but its capabilities are a bit limited. <strong>Marked</strong> gives you nicer previews with multiple styles to choose from, word counts, hyperlink validation, and some other stuff that definitely justifies its $3.99 price.</p> <p>To use <strong>Marked</strong> with <strong>RStudio</strong> just drag the <code>.Rnw</code> or <code>.md</code> file you're working on in <strong>RStudio</strong> on top of the <strong>Marked</strong> icon. It will update any time you save or compile the files.</p> <p>(Oh, note I think <strong>Marked</strong> is Mac only. Also, I have no affiliation with <strong>RStudio</strong> or <strong>Marked</strong>, I just really like them.)</p><div class="blogger-post-footer"><img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/36784551-2797088354708948337?l=christophergandrud.blogspot.com' alt='' /></div>
<p class="syndicated-attribution"><div style="border: 1px solid; background: none repeat scroll 0 0 #EDEDED; margin: 1px; font-size: 13px;">
<div style="text-align: center;">To <strong>leave a comment</strong> for the author, please follow the link and comment on his blog: <strong><a href="http://christophergandrud.blogspot.com/2012/05/dynamic-content-with-rstudio-markdown.html"> Christopher Gandrud</a></strong>.</div>
<hr />
<a href="http://www.r-bloggers.com/">R-bloggers.com</a> offers <strong><a href="http://feedburner.google.com/fb/a/mailverify?uri=RBloggers">daily e-mail updates</a></strong> about <a title="The R Project for Statistical Computing" href="http://www.r-project.org/">R</a> news and <a title="R tutorials" href="http://www.r-bloggers.com/?s=tutorial">tutorials</a> on topics such as: visualization (<a title="ggplot and ggplot2 tutorials" href="http://www.r-bloggers.com/?s=ggplot2">ggplot2</a>, <a title="Boxplots using lattice and ggplot2 tutorials" href="http://www.r-bloggers.com/?s=boxplot">Boxplots</a>, <a title="Maps and gis" href="http://www.r-bloggers.com/?s=map">maps</a>, <a title="Animation in R" href="http://www.r-bloggers.com/?s=animation">animation</a>), programming (<a title="RStudio IDE for R" href="http://www.r-bloggers.com/?s=RStudio">RStudio</a>, <a title="Sweave and literate programming" href="http://www.r-bloggers.com/?s=sweave">Sweave</a>, <a title="LaTeX in R" href="http://www.r-bloggers.com/?s=LaTeX">LaTeX</a>, <a title="SQL and databases" href="http://www.r-bloggers.com/?s=SQL">SQL</a>, <a title="Eclipse IDE for R" href="http://www.r-bloggers.com/?s=eclipse">Eclipse</a>, <a title="git and github, Version Control System" href="http://www.r-bloggers.com/?s=git">git</a>, <a title="Large data in R using Hadoop" href="http://www.r-bloggers.com/?s=hadoop">hadoop</a>, <a title="Web Scraping of google, facebook, yahoo, twitter and more using R" href="http://www.r-bloggers.com/?s=Web+Scraping">Web Scraping</a>) statistics (<a title="Regressions and ANOVA analysis tutorials" href="http://www.r-bloggers.com/?s=regression">regression</a>, <a title="principal component analysis tutorial" href="http://www.r-bloggers.com/?s=PCA">PCA</a>, <a title="Time series" href="http://www.r-bloggers.com/?s=time+series">time series</a>,<a title="ecdf" href="http://www.r-bloggers.com/?s=ecdf">ecdf</a>, <a title="finance trading" href="http://www.r-bloggers.com/?s=trading">trading</a>) and more...
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		<title>Using R to graph a subject trend in PubMed</title>
		<link>http://www.r-bloggers.com/using-r-to-graph-a-subject-trend-in-pubmed/</link>
		<comments>http://www.r-bloggers.com/using-r-to-graph-a-subject-trend-in-pubmed/#comments</comments>
		<pubDate>Tue, 15 May 2012 23:13:00 +0000</pubDate>
		<dc:creator>David Ruau</dc:creator>
				<category><![CDATA[R bloggers]]></category>
		<category><![CDATA[R]]></category>

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		<description><![CDATA[The traditional way to show that your topic is worth studying in front of an audience is to show the state of the field based on a literature review. This is especially true if your subject is obscure except to a handful of scientists in the world.I wa...]]></description>
			<content:encoded><![CDATA[<p class="syndicated-attribution"><div style="border: 1px solid; background: none repeat scroll 0 0 #EDEDED; margin: 1px; font-size: 12px;">
(This article was first published on  <strong><a href="http://brainchronicle.blogspot.com/2012/05/using-r-to-graph-subject-trend-in.html"> Brain Chronicle</a></strong>, and kindly contributed to <a href="http://www.r-bloggers.com/">R-bloggers)</a>      
</div></p>
The traditional way to show that your topic is worth studying in front of an audience is to show the state of the field based on a literature review. This is especially true if your subject is obscure except to a handful of scientists in the world.<br />I was confronted with this problem more than once and the last time I decided to plot the state-of-the-field using a few scripts.<br />I wrote three scripts for that: pubmed_trend.r that take your PubMed query and send it to the NCBI using the Eutils tools (Perl script). Then I plot the results. The details of the scripts is below but here how you create your trend.<br />Here we plot the trend for the number of publications per year for papers annotated with MeSH terms for "sex characteristics" and "pain" and compare this search to the number of publication/year for "sex characteristics" and "Analgesics". We will run this search between 1970 and 2011. <script src="https://gist.github.com/2705715.js?file=pubmed_pain.r"></script>And here is the plot. <br /><div class="separator" style="clear: both; text-align: center;"><a href="http://1.bp.blogspot.com/-cQW14gE_7Ls/T7LevvY2ibI/AAAAAAAABvE/FxnwDn1Du2c/s1600/sex_pain.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;" ref="nofollow" target="_blank"><img border="0" height="400" src="http://1.bp.blogspot.com/-cQW14gE_7Ls/T7LevvY2ibI/AAAAAAAABvE/FxnwDn1Du2c/s400/sex_pain.jpg" width="400" /></a></div>What we see here is that the number of publications per year talking about sex difference and pain or analgesics is growing but the number of publication per year is still small and more research is needed.<br />...and you are good to go, your talk is <a href="http://media.tumblr.com/tumblr_lt77phjQ9f1qdlkgg.gif" ref="nofollow" target="_blank">launch</a><br /><br />Here is the details of the scripts and functions. The pubmed_trend.r take a query string as you would type it in the search box through the web interface (space have to be replaced by '+').<br /><script src="https://gist.github.com/2705578.js?file=pubmed_trend.r"></script>The Perl script is straight forward and return an XML file that is parsed by the XML library in R. <script src="https://gist.github.com/2705578.js?file=pubmed_trend.pl"></script>And here is the plot function using barplot. <script src="https://gist.github.com/2705679.js?file=pubmed_barplot"></script><div class="blogger-post-footer"><img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/1861070732189366413-9087882979887814675?l=brainchronicle.blogspot.com' alt='' /></div>
<p class="syndicated-attribution"><div style="border: 1px solid; background: none repeat scroll 0 0 #EDEDED; margin: 1px; font-size: 13px;">
<div style="text-align: center;">To <strong>leave a comment</strong> for the author, please follow the link and comment on his blog: <strong><a href="http://brainchronicle.blogspot.com/2012/05/using-r-to-graph-subject-trend-in.html"> Brain Chronicle</a></strong>.</div>
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		<title>How long before R overtakes SAS and SPSS?</title>
		<link>http://www.r-bloggers.com/how-long-before-r-overtakes-sas-and-spss/</link>
		<comments>http://www.r-bloggers.com/how-long-before-r-overtakes-sas-and-spss/#comments</comments>
		<pubDate>Tue, 15 May 2012 22:37:34 +0000</pubDate>
		<dc:creator>David Smith</dc:creator>
				<category><![CDATA[R bloggers]]></category>
		<category><![CDATA[R]]></category>

		<guid isPermaLink="false">http://www.r-bloggers.com/?guid=256ae4211d148acf081e4387dbaf0c2c</guid>
		<description><![CDATA[Based on an analysis of Google Scholar data on usage of statistical software, Bob Muenchen makes a forecast: R will overtake SAS and SPSS in 2015. Forecasting is extrapolation — always a tricky business — so Bob also provides these qualitative reasons why R will continue to grow at the expense of SAS and SPSS: The continued rapid growth in add-on packages (Figure 10) The attraction of R’s powerful language The near monopoly R has on the latest analytic methods Its free price The freedom to teach with real-world examples from outside organizations, which is forbidden to academics by SAS...]]></description>
			<content:encoded><![CDATA[<p class="syndicated-attribution"><div style="border: 1px solid; background: none repeat scroll 0 0 #EDEDED; margin: 1px; font-size: 12px;">
(This article was first published on  <strong><a href="http://blog.revolutionanalytics.com/2012/05/how-long-before-r-overtakes-sas-and-spss.html"> Revolutions</a></strong>, and kindly contributed to <a href="http://www.r-bloggers.com/">R-bloggers)</a>      
</div></p>

<div><p>Based on an analysis of Google Scholar data on usage of statistical software, Bob Muenchen makes a forecast: <a href="http://r4stats.com/2012/05/09/beginning-of-the-end/" ref="nofollow" target="_blank">R will overtake SAS and SPSS in 2015</a>. Forecasting is extrapolation — always a tricky business — so Bob also provides these qualitative reasons why <a href="http://www.revolutionanalytics.com/what-is-open-source-r/" ref="nofollow" target="_blank">R</a> will continue to grow at the expense of SAS and SPSS:</p>
<ul>
<li>The continued rapid growth in add-on packages (<a href="http://r4stats.com/articles/popularity/" ref="nofollow" target="_blank">Figure 10</a>)</li>
<li>The attraction of R’s powerful language</li>
<li>The near monopoly R has on the latest analytic methods</li>
<li>Its free price</li>
<li>The freedom to teach with real-world examples from outside organizations, which is forbidden to academics by SAS and SPSS licenses (it benefits those organizations, so the vendors say they should have their own software license).</li>
</ul>
<p>See how Bob comes up with this forecast (using R, of course!) at the link below.</p>
<p>r4stats.com: <a href="http://r4stats.com/2012/05/09/beginning-of-the-end/" ref="nofollow" target="_blank">Will 2015 be the Beginning of the End for SAS and SPSS?</a></p></div>

<p class="syndicated-attribution"><div style="border: 1px solid; background: none repeat scroll 0 0 #EDEDED; margin: 1px; font-size: 13px;">
<div style="text-align: center;">To <strong>leave a comment</strong> for the author, please follow the link and comment on his blog: <strong><a href="http://blog.revolutionanalytics.com/2012/05/how-long-before-r-overtakes-sas-and-spss.html"> Revolutions</a></strong>.</div>
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		<title>Interactive reports in R with knitr and RStudio</title>
		<link>http://www.r-bloggers.com/interactive-reports-in-r-with-knitr-and-rstudio/</link>
		<comments>http://www.r-bloggers.com/interactive-reports-in-r-with-knitr-and-rstudio/#comments</comments>
		<pubDate>Tue, 15 May 2012 21:36:00 +0000</pubDate>
		<dc:creator>Markus Gesmann</dc:creator>
				<category><![CDATA[R bloggers]]></category>
		<category><![CDATA[googleVis]]></category>
		<category><![CDATA[knitr]]></category>
		<category><![CDATA[R]]></category>
		<category><![CDATA[R in Finance]]></category>
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		<description><![CDATA[Last Saturday I met the guys from RStudio at the R in Finance conference in Chicago. I was curious to find out what RStudio could offer. In the past I have used mostly Emacs + ESS for editing R files. Well, and what a surprise it was. JJ, Joe and Josh ...]]></description>
			<content:encoded><![CDATA[<p class="syndicated-attribution"><div style="border: 1px solid; background: none repeat scroll 0 0 #EDEDED; margin: 1px; font-size: 12px;">
(This article was first published on  <strong><a href="http://lamages.blogspot.com/2012/05/interactive-reports-in-r-with-knitr-and.html"> mages' blog</a></strong>, and kindly contributed to <a href="http://www.r-bloggers.com/">R-bloggers)</a>      
</div></p>
<p>Last Saturday I met the guys from <a href="http://rstudio.org/" ref="nofollow" target="_blank">RStudio</a> at the <a href="http://www.rinfinance.com/" ref="nofollow" target="_blank">R in Finance</a> conference in Chicago. I was curious to find out what RStudio could offer. In the past I have used mostly <a href="https://www.gnu.org/software/emacs/" ref="nofollow" target="_blank">Emacs</a> + <a href="http://ess.r-project.org/" ref="nofollow" target="_blank">ESS</a> for editing R files. Well, and what a surprise it was. JJ, Joe and Josh showed me a preview of <a href="http://blog.rstudio.org/2012/05/14/rstudio-v096/" ref="nofollow" target="_blank">version 0.96</a> of their software, which adds a close integration of <a href="http://www.statistik.lmu.de/~leisch/Sweave/" ref="nofollow" target="_blank">Sweave</a> and <a href="http://yihui.name/knitr/" ref="nofollow" target="_blank">knitr</a> to RStudio, helping to create dynamic web reports with the new R Markdown and R HTML formats more easily. <br /></p><table align="center" cellpadding="0" cellspacing="0" class="tr-caption-container" style="margin-left: auto; margin-right: auto; text-align: center;"><tbody><tr><td style="text-align: center;"><a href="http://1.bp.blogspot.com/-29GX79YO5Po/T7KVGcOfCwI/AAAAAAAAARI/1MWSONLG7SY/s1600/RStudio.png" imageanchor="1" style="margin-left: auto; margin-right: auto;" ref="nofollow" target="_blank"><img border="0" height="225" src="http://1.bp.blogspot.com/-29GX79YO5Po/T7KVGcOfCwI/AAAAAAAAARI/1MWSONLG7SY/s320/RStudio.png" width="320" /></a></td></tr><tr><td class="tr-caption" style="text-align: center;">Screen shot of RStudio with a knitr file (*.Rmd) in the top left window. <br />Notice also the integrated <i>knitr</i> button.</td></tr></tbody></table><p>You probably have come across Sweave in the past, but <i>knitr</i> is a fairly new package by <a href="http://yihui.name/" ref="nofollow" target="_blank">Yihui Xie</a> that brings <a href="http://en.wikipedia.org/wiki/Literate_programming" ref="nofollow" target="_blank">literate programming</a> to a new level. In particular the <a href="http://en.wikipedia.org/wiki/Markdown" ref="nofollow" target="_blank">markdown</a> approach allows me to create web content really quickly, without worrying to much about layout and R formatting. I begin to wonder if PDF and paper will be replaced by tablets and HTML5 in the future.<br /></p><p>Here is a simple example. The <i>knitr</i> <a href="https://gist.github.com/2704646" ref="nofollow" target="_blank">source code</a> is available on <a href="https://gist.github.com/2704646" ref="nofollow" target="_blank">Github</a>.</p><iframe src="http://dl.dropbox.com/u/7586336/blogger/knitr/googleVis_with_knitr_and_RStudio.html" width=595 height=2700 frameborder="0">Loading ...</iframe><br /><div class="blogger-post-footer"><img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/9065396442320388284-2135778244633380580?l=lamages.blogspot.com' alt='' /></div>
<p class="syndicated-attribution"><div style="border: 1px solid; background: none repeat scroll 0 0 #EDEDED; margin: 1px; font-size: 13px;">
<div style="text-align: center;">To <strong>leave a comment</strong> for the author, please follow the link and comment on his blog: <strong><a href="http://lamages.blogspot.com/2012/05/interactive-reports-in-r-with-knitr-and.html"> mages' blog</a></strong>.</div>
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		<title>Will 2015 be the Beginning of the End for SAS and SPSS?</title>
		<link>http://www.r-bloggers.com/will-2015-be-the-beginning-of-the-end-for-sas-and-spss/</link>
		<comments>http://www.r-bloggers.com/will-2015-be-the-beginning-of-the-end-for-sas-and-spss/#comments</comments>
		<pubDate>Tue, 15 May 2012 20:36:19 +0000</pubDate>
		<dc:creator>r4stats</dc:creator>
				<category><![CDATA[R bloggers]]></category>
		<category><![CDATA[analytics]]></category>
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		<category><![CDATA[r-project]]></category>
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		<category><![CDATA[SPSS]]></category>
		<category><![CDATA[statistics]]></category>

		<guid isPermaLink="false">http://r4stats.com/?p=666</guid>
		<description><![CDATA[Learning to use a data analysis tool well takes significant effort, so people tend to continue using the tool they learned in college for much of their careers. As a result, the software used by professors and their students is &#8230; <a href="http://r4stats.com/2012/05/09/beginning-of-the-end/">Continue reading <span>&#8594;</span></a><img alt="" border="0" src="http://stats.wordpress.com/b.gif?host=r4stats.com&#38;blog=35357879&#38;post=666&#38;subd=r4stats&#38;ref=&#38;feed=1" width="1" height="1" />]]></description>
			<content:encoded><![CDATA[<p class="syndicated-attribution"><div style="border: 1px solid; background: none repeat scroll 0 0 #EDEDED; margin: 1px; font-size: 12px;">
(This article was first published on  <strong><a href="http://r4stats.com/2012/05/09/beginning-of-the-end/"> r4stats.com » R</a></strong>, and kindly contributed to <a href="http://www.r-bloggers.com/">R-bloggers)</a>      
</div></p>
<p>Learning to use a data analysis tool well takes significant effort, so people tend to continue using the tool they learned in college for much of their careers. As a result, the software used by professors and their students is likely to predict what the next generation of analysts will use for years to come. I track this trend, and many others, in my article <a title="The Popularity of Data Analysis Software" href="http://r4stats.com/articles/popularity/" ref="nofollow" target="_blank"><em>The Popularity of Data Analysis Software</em></a>. In the latest update (4/13/2012) I forecast that, if current trends continued, the use of the R software would exceed that of SAS for scholarly applications in 2015. That was based on the data shown in Figure 7a, which I repeat here:</p>
<p><a href="http://r4stats.files.wordpress.com/2012/04/fig_7a_scholarlyimpactbig6.png" ref="nofollow" target="_blank"><img class="aligncenter size-full wp-image-643" title="Fig_7a_ScholarlyImpactBig6" src="http://r4stats.files.wordpress.com/2012/04/fig_7a_scholarlyimpactbig6.png?w=640&h=640" alt="" width="640" height="640" /></a>Let&#8217;s take a more detailed look at what the future may hold for R, SAS and SPSS Statistics.</p>
<p>Here is the data from Google Scholar:</p>
<pre>         R   SAS   SPSS
1995     8  8620   6450
1996     2  8670   7600
1997     6 10100   9930
1998    13 10900  14300
1999    26 12500  24300
2000    51 16800  42300
2001   133 22700  68400
2002   286 28100  88400
2003   627 40300  78600
2004  1180 51400 137000
2005  2180 58500 147000
2006  3430 64400 142000
2007  5060 62700 131000
2008  6960 59800 116000
2009  9220 52800  61400
2010 11300 43000  44500
2011 14600 32100  32000</pre>
<p><strong>ARIMA Forecasting</strong></p>
<p>We can forecast the use of R using <a href="http://robjhyndman.com/software/forecast/" ref="nofollow" target="_blank">Rob Hyndman&#8217;s</a> handy auto.arima function to forecast five years into the future:</p>
<p><pre class="brush: r;">
&gt; library(&quot;forecast&quot;)

&gt; R_fit &lt;- auto.arima(R)

&gt; R_forecast &lt;- forecast(R_fit, h=5)

&gt; R_forecast

   Point Forecast Lo 80 Hi 80 Lo 95 Hi 95
18          18258 17840 18676 17618 18898
19          22259 21245 23273 20709 23809
20          26589 24768 28409 23805 29373
21          31233 28393 34074 26889 35578
22          36180 32102 40258 29943 42417
</pre></p>
<p>We see that even if the use of SAS and SPSS were to remain at their current levels, R use would surpass their use in 2016 (<em>Point Forecast</em> column where 18-22 represent years 2012 -2016).</p>
<p>If we follow the same steps for SAS we get:</p>
<p><pre class="brush: r;">
&gt; SAS_fit &lt;- auto.arima(SAS)

&gt; SAS_forecast &lt;- forecast(SAS_fit, h=5)

&gt; SAS_forecast

   Point Forecast     Lo 80   Hi 80    Lo 95 Hi 95
18          21200  16975.53 25424.5  14739.2 27661
19          10300    853.79 19746.2  -4146.7 24747
20           -600 -16406.54 15206.5 -24774.0 23574
21         -11500 -34638.40 11638.4 -46887.1 23887
22         -22400 -53729.54  8929.5 -70314.4 25514
</pre></p>
<p>It appears that if the use of SAS continues to decline at its precipitous rate, all scholarly use of it will stop in 2014 (the number of articles published can&#8217;t be less than zero, so view the negatives as zero). I would bet Mitt Romney <a href="http://www.washingtonpost.com/blogs/election-2012/post/mitt-romney-challenges-rick-perry-to-10000-bet-in-gop-debate/2011/12/11/gIQAudrBnO_blog.html" ref="nofollow" target="_blank">$10,000</a> that that is not going to happen!</p>
<p>I find the SPSS prediction the most interesting:</p>
<p><pre class="brush: r;">
&gt; SPSS_fit &lt;- auto.arima(SPSS)

&gt; SPSS_forecast &lt;- forecast(SPSS_fit, h=5)

&gt; SPSS_forecast

   Point Forecast   Lo 80 Hi 80   Lo 95  Hi 95
18        13653.2  -16301 43607  -32157  59463
19        -4693.6  -57399 48011  -85299  75912
20       -23040.4 -100510 54429 -141520  95439
21       -41387.2 -145925 63151 -201264 118490
22       -59734.0 -193590 74122 -264449 144981
</pre></p>
<p>The forecast has taken a logical approach of focusing on the steeper decline from 2005 through 2010 and predicting that this year (2012) is the last time SPSS will see use in scholarly publications. However the part of the graph that I find most interesting is the shift from 2010 to 2011, which shows SPSS use still declining but at a much slower rate.</p>
<p>Any forecasting book will warn you of the dangers of looking too far beyond the data and I think these forecasts do just that. The 2015 figure in the <em>Popularity</em> paper and in the title of this blog post came from an exponential smoothing approach that did not match the rate of acceleration as well as the ARIMA approach does.</p>
<p><strong>Colbert Forecasting</strong></p>
<p>While ARIMA forecasting has an impressive mathematical foundation it&#8217;s always fun to follow <a href="http://www.colbertnation.com/" ref="nofollow" target="_blank">Stephen Colbert&#8217;s</a> approach: go from the gut. So now I&#8217;ll present the future of analytics software that must be true, because it feels so right to me personally. This analysis has Colbert&#8217;s most important attribute: <a href="http://en.wikipedia.org/wiki/Truthiness" ref="nofollow" target="_blank">truthiness</a>.</p>
<p>The growth in R&#8217;s use in scholarly work will continue for two more years at which point it will level off at around 25,000 articles in 2014.This growth will be driven by:</p>
<ul>
<li>The continued rapid growth in add-on packages (<a href="http://r4stats.com/articles/popularity/" ref="nofollow" target="_blank">Figure 10</a>)</li>
<li>The attraction of R&#8217;s powerful language</li>
<li>The near monopoly R has on the latest analytic methods</li>
<li>Its free price</li>
<li>The freedom to teach with real-world examples from outside organizations, which is forbidden to academics by SAS and SPSS licenses (it benefits those organizations, so the vendors say they should have their own software license).</li>
</ul>
<p>What will slow R&#8217;s growth is its lack of a graphical user interface that:</p>
<ul>
<li>Is powerful</li>
<li>Is easy to use</li>
<li>Provides journal style output in word processor format</li>
<li>Is standard, i.e. widely accepted as <em>The One to Use</em></li>
<li>Is open source</li>
</ul>
<p>While programming has important advantages over GUI use, many people will not take the time needed to learn to program. Therefore they rarely come to fully understand those advantages. Conversely, programmers seldom take the time to fully master a GUI and so often underestimate its capabilities. Regardless of which is best, GUI users far outnumber programmers and, until resolved, this will limit R&#8217;s long term growth. There are GUIs for R, but so many to choose from that none becomes the clear leader (Deducer, R Commander, Rattle, Red-R, at least two from commercial companies and still more <a href="http://en.wikipedia.org/wiki/R_(programming_language)#Graphical_user_interfaces" ref="nofollow" target="_blank">here</a>.) If from this &#8220;GUI chaos&#8221; a clear leader were to emerge, then R could continue its rapid growth and end up as the most used package.</p>
<p>The use of SAS for scholarly work will continue to decline until it matches R at the 25,000 level. This is caused by competition from R and other packages (notably Stata) but also by SAS Instute&#8217;s self-inflicted GUI chaos.  For years they have offered too many GUIs such as SAS/Assist, SAS/Insight, IML/Studio, the Analyst application, Enterprise Guide, Enterprise Miner and  even JMP (which runs SAS nicely in recent versions). Professors looking to meet student demand for greater ease of use could not decide what to teach so they continued teaching SAS as a programming language. Even now that Enterprise Guide has evolved into a good GUI, many SAS users do not know what it is. If SAS Institute were to completely replace their default Display Manager System with Enterprise Guide, they could bend the curve and end up at a higher level of perhaps 27,000.</p>
<p>The use of SPSS for scholarly work will decline only slightly this year and will level off in 2013 because:</p>
<ul>
<li>The people who needed advanced methods and were not happy <a title="Calling R from Other Software" href="http://r4stats.com/articles/calling-r/" ref="nofollow" target="_blank">calling R functions from within SPSS</a> have already switched to R or Stata</li>
<li>The people who like to program and want a more flexible language than SPSS offers have already switched to R or Stata</li>
<li>The people who needed a more advanced GUI have already switched to JMP</li>
</ul>
<p>The GUI users will stick with SPSS until a GUI as good (or close to as good) comes to R and becomes widely accepted. At The University of Tennessee where I work, that&#8217;s the great majority of SPSS users.</p>
<p>Stata&#8217;s growth will level off in 2013 at level that will leave it in fourth place. The other packages shown in <a title="The Popularity of Data Analysis Software" href="http://r4stats.com/articles/popularity/" ref="nofollow" target="_blank">Figure 7b</a> will also level off around the same time, roughly maintaining their current place in the rankings. A possible exception is JMP, whose interface is radically superior to the the others for exploratory analysis. Its use could continue to grow, perhaps even replacing Stata for fourth place.</p>
<p>The future of Enterprise Miner and SPSS Modeler are tied to the success of each company&#8217;s more mainstream products, SAS and SPSS Statistics respectively. Use of those products is generally limited to one university class in data mining, while the other software discussed here is widely used in many classes.</p>
<p>So there you have it: the future of analytics revealed. No doubt each reader has found a wide range of things to disagree with, so I encourage you to follow the detailed blog at <a href="http://librestats.com/2012/04/12/statistical-software-popularity-on-google-scholar/" ref="nofollow" target="_blank">Librestats</a> to collect your own data from Google Scholar and do your own set of forecasts. Or simply go from the gut!</p>
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		<title>Forthcoming R User Meetings</title>
		<link>http://www.r-bloggers.com/forthcoming-r-user-meetings/</link>
		<comments>http://www.r-bloggers.com/forthcoming-r-user-meetings/#comments</comments>
		<pubDate>Tue, 15 May 2012 20:35:47 +0000</pubDate>
		<dc:creator>Tal Galili</dc:creator>
				<category><![CDATA[R guest posts]]></category>

		<guid isPermaLink="false">http://www.r-bloggers.com/?p=61805</guid>
		<description><![CDATA[Two R User Group meetings are happening soon thanks to the support of Mango-solutions (one of R-bloggers&#8217; long term sponsors).  Details below: &#160; 1)      ZurichR – Wednesday 23rd May 2012 (www.zurichr.org) ZurichR is a free networking event for R users sponsored by Mango Solutions and ETH Zurich All welcome to attend.  Please confirm attendance in advance to zurichr@mango-solutions.com Time:       6.30pm &#8211; 9.30 pm Place:      ETH Zurich, Room HG F 50.3, Rämistrasse 101, 8092 Zurich Presentations: ·         R with COM; the dark side of .NET &#8211; John James, Mango Solutions ·         Stability Analytics of Financial Time Series &#8211; Diethelm Wuertz, ETH ·         Transparent Investment Management – Simon Otziger, Corepoint Capital &#160; 2)      LondonR – 19th June 2012 (www.londonr.org) &#160; LondonR is a free networking event for R users sponsored by Mango Solutions All welcome to attend.  Please confirm attendance in advance to londonr@mango-solutions.com Venue:  The Counting House, 50 Cornhill, London, London EC3V 3PD (the meeting room is upstairs) Time:     6pm &#8211; 9.30 pm Presentations: ·         Writing R for Dummies – Andrie De Vries ·         Dynamical Systems in R with simecol – Markus Gesmann ·         News from data.table 1.6, 1.7 and 1.8 – Matthew Dowle ·         Converting S Plus Applications to R – Andy Nicholls &#160; &#160; &#160; &#160;]]></description>
			<content:encoded><![CDATA[<p>Two R User Group meetings are happening soon thanks to the support of <a href="http://www.mango-solutions.com/" ref="nofollow" target="_blank">Mango-solutions</a> (one of R-bloggers&#8217; long term sponsors).  Details below:</p>
<p>&nbsp;</p>
<p><strong>1)      </strong><strong>ZurichR – Wednesday 23<sup>rd</sup> May 2012 (<a href="http://www.zurichr.org/" target="_blank" ref="nofollow">www.zurichr.org</a>)</strong></p>
<p>ZurichR is a free networking event for R users sponsored by Mango Solutions and ETH Zurich</p>
<p>All welcome to attend.  Please confirm attendance in advance to <a href="mailto:zurichr@mango-solutions.com" target="_blank" ref="nofollow">zurichr@mango-solutions.com</a></p>
<p>Time:       6.30pm &#8211; 9.30 pm</p>
<p>Place:      ETH Zurich, Room HG F 50.3, Rämistrasse 101, 8092 Zurich</p>
<p>Presentations:</p>
<ul>
<li>·         R with COM; the dark side of .NET &#8211; John James, Mango Solutions</li>
<li>·         Stability Analytics of Financial Time Series &#8211; Diethelm Wuertz, ETH</li>
<li>·         Transparent Investment Management – Simon Otziger, Corepoint Capital</li>
</ul>
<p>&nbsp;</p>
<p><strong>2)      </strong><strong>LondonR – 19<sup>th</sup> June 2012 (<a href="http://www.londonr.org/" target="_blank" ref="nofollow">www.londonr.org</a>)</strong></p>
<p>&nbsp;</p>
<p>LondonR is a free networking event for R users sponsored by Mango Solutions</p>
<p>All welcome to attend.  Please confirm attendance in advance to <a href="mailto:londonr@mango-solutions.com" target="_blank" ref="nofollow">londonr@mango-solutions.com</a></p>
<p><strong>Venue</strong>:  The Counting House, 50 Cornhill, London, London EC3V 3PD (the meeting room is upstairs)</p>
<p><strong>Time</strong>:     6pm &#8211; 9.30 pm</p>
<p><strong>Presentations</strong>:</p>
<ul>
<li>·         Writing R for Dummies – Andrie De Vries</li>
<li>·         Dynamical Systems in R with simecol – Markus Gesmann</li>
<li>·         News from data.table 1.6, 1.7 and 1.8 – Matthew Dowle</li>
<li>·         Converting S Plus Applications to R – Andy Nicholls</li>
</ul>
<p>&nbsp;</p>
<p>&nbsp;</p>
<p>&nbsp;</p>
<p>&nbsp;</p>

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		<title>Skew of Bonds</title>
		<link>http://www.r-bloggers.com/skew-of-bonds/</link>
		<comments>http://www.r-bloggers.com/skew-of-bonds/#comments</comments>
		<pubDate>Tue, 15 May 2012 18:22:00 +0000</pubDate>
		<dc:creator>klr</dc:creator>
				<category><![CDATA[R bloggers]]></category>
		<category><![CDATA[bonds]]></category>
		<category><![CDATA[R]]></category>
		<category><![CDATA[skew]]></category>

		<guid isPermaLink="false">http://www.r-bloggers.com/?guid=d1353bc2ffdc96715b211a0adb842667</guid>
		<description><![CDATA[As the researchpuzzler highlights in “a bad bet”, US bonds were a popular subject at the CFA Institute Annual Conference.&#160; While US Bonds have been in an amazing 30 year run (see previous posts Lattice Explore Bonds, Bond Market as a Casino Ga...]]></description>
			<content:encoded><![CDATA[<p class="syndicated-attribution"><div style="border: 1px solid; background: none repeat scroll 0 0 #EDEDED; margin: 1px; font-size: 12px;">
(This article was first published on  <strong><a href="http://timelyportfolio.blogspot.com/2012/05/skew-of-bonds.html"> Timely Portfolio</a></strong>, and kindly contributed to <a href="http://www.r-bloggers.com/">R-bloggers)</a>      
</div></p>
<p>As the researchpuzzler highlights in <a href="http://rp-pix.com/" ref="nofollow" target="_blank">“a bad bet”</a>, US bonds were a popular subject at the CFA Institute Annual Conference.&nbsp; While US Bonds have been in an amazing 30 year run (see previous posts <a href="http://timelyportfolio.blogspot.com/2011/12/lattice-explore-bonds.html" ref="nofollow" target="_blank">Lattice Explore Bonds</a>, <a href="http://timelyportfolio.blogspot.com/2011/04/bond-market-as-casino-game-part-1.html" ref="nofollow" target="_blank">Bond Market as a Casino Game Part 1</a>, <a href="http://timelyportfolio.blogspot.com/search/label/Bonds%20Tumble%20and%20Questions%20Start%20Getting%20Asked" ref="nofollow" target="_blank">Calmar Ratio 1.37 over the past 20 years</a>), I think many positive skew-chasing market participants are not aware of the frequency of negative skew in bond returns.&nbsp; As a public service, I thought I should issue a negative skew alert.</p> <table style="width: auto"> <tbody> <tr> <td><a href="https://picasaweb.google.com/lh/photo/Yc5brw94bSWzKFugJoTMU9MTjNZETYmyPJy0liipFm0?feat=embedwebsite" ref="nofollow" target="_blank"><img src="https://lh4.googleusercontent.com/-urc9r7BB5AU/T7KeBaWQXbI/AAAAAAACjVw/wSfQ8NgsmpI/s800/rolling%2520bond%2520skew.png" width="640" height="520"></a></td></tr> <tr> <td style="text-align: right; font-family: arial,sans-serif; font-size: 11px">From <a href="https://picasaweb.google.com/115099029813395778077/TimelyPortfolio02?authuser=0&amp;feat=embedwebsite" ref="nofollow" target="_blank">TimelyPortfolio</a></td></tr></tbody></table> <p><a href="https://gist.github.com/2703904" ref="nofollow" target="_blank">R code from GIST:</a></p><script src="https://gist.github.com/2703904.js"> </script>  <div class="blogger-post-footer"><img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/7630810606654250077-8383129064394889780?l=timelyportfolio.blogspot.com' alt='' /></div>
<p class="syndicated-attribution"><div style="border: 1px solid; background: none repeat scroll 0 0 #EDEDED; margin: 1px; font-size: 13px;">
<div style="text-align: center;">To <strong>leave a comment</strong> for the author, please follow the link and comment on his blog: <strong><a href="http://timelyportfolio.blogspot.com/2012/05/skew-of-bonds.html"> Timely Portfolio</a></strong>.</div>
<hr />
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		<title>Improving script_002: “Monitor”</title>
		<link>http://www.r-bloggers.com/improving-script_002-%e2%80%9cmonitor%e2%80%9d/</link>
		<comments>http://www.r-bloggers.com/improving-script_002-%e2%80%9cmonitor%e2%80%9d/#comments</comments>
		<pubDate>Tue, 15 May 2012 17:45:00 +0000</pubDate>
		<dc:creator>jrcuesta</dc:creator>
				<category><![CDATA[R bloggers]]></category>
		<category><![CDATA["R" Chemometrics]]></category>

		<guid isPermaLink="false">http://www.r-bloggers.com/?guid=ef8217287719378fe95b5978fb5c1b25</guid>
		<description><![CDATA[I read in an article that Ian Cowe said that what normally chemometricians do is to look to the graphics, of course interpret those graphics. So I still go on trying to develop a function can help me to understand the graphics and all the statistics th...]]></description>
			<content:encoded><![CDATA[<p class="syndicated-attribution"><div style="border: 1px solid; background: none repeat scroll 0 0 #EDEDED; margin: 1px; font-size: 12px;">
(This article was first published on  <strong><a href="http://nir-quimiometria.blogspot.com/2012/05/improving-script002-monitor.html"> NIR-Quimiometría</a></strong>, and kindly contributed to <a href="http://www.r-bloggers.com/">R-bloggers)</a>      
</div></p>
<div class="MsoNoSpacing" style="margin: 0cm 0cm 0pt;"><span style="font-family: &quot;Times New Roman&quot;, &quot;serif&quot;; font-size: 12pt;">I read in an article that Ian Cowe said that what normally chemometricians do is to look to the graphics, of course interpret those graphics. So I still go on trying to develop a function can help me to understand the graphics and all the statistics there are behind.</span></div><div class="MsoNoSpacing" style="margin: 0cm 0cm 0pt;"><span style="font-family: &quot;Times New Roman&quot;, &quot;serif&quot;; font-size: 12pt;">I add some more lines to the monitor function:</span><span style="font-family: &quot;Courier New&quot;;"></span></div><div class="MsoNoSpacing" style="margin: 0cm 0cm 0pt;"><span style="color: #000099; font-family: &quot;Courier New&quot;;">plot(x~y,main="X-Y plot",xlab="predicted",ylab="reference")</span></div><div class="MsoNoSpacing" style="margin: 0cm 0cm 0pt;"><span style="color: #000099; font-family: &quot;Courier New&quot;;">abline(0,1,col="blue")</span></div><div class="MsoNoSpacing" style="margin: 0cm 0cm 0pt;"><span style="color: #000099; font-family: &quot;Courier New&quot;;">abline(intercept,slope,col="red")</span></div><div class="MsoNoSpacing" style="margin: 0cm 0cm 0pt;"><span style="color: #000099; font-family: &quot;Courier New&quot;;">abline(intercept+(2.5*sep),slope,col="red",lty=4)</span></div><div class="MsoNoSpacing" style="margin: 0cm 0cm 0pt;"><span style="color: #000099; font-family: &quot;Courier New&quot;;">abline(intercept-(2.5*sep),slope,col="red",lty=4)</span></div><div class="MsoNoSpacing" style="margin: 0cm 0cm 0pt;"><span style="font-family: &quot;Times New Roman&quot;, &quot;serif&quot;; font-size: 12pt;">I can do the same for the residual plot. </span></div><div class="MsoNoSpacing" style="margin: 0cm 0cm 0pt;"><span style="font-family: &quot;Times New Roman&quot;, &quot;serif&quot;; font-size: 12pt;">There are two warning lines which advice if the residual exceeds 2,5*SEP value. That is the T value warning limit.</span></div><div class="MsoNoSpacing" style="margin: 0cm 0cm 0pt;"><span style="font-family: &quot;Times New Roman&quot;, &quot;serif&quot;; font-size: 12pt;">Another line can be add, called the T value action limit (3*SEP).</span></div><div class="MsoNoSpacing" style="margin: 0cm 0cm 0pt;"><span style="font-family: &quot;Times New Roman&quot;, &quot;serif&quot;; font-size: 12pt;">Graphics show the 0-1 abline (blue) and the calculated slope-intercept abline (red). Limits are with dashed red lines.</span></div><div class="MsoNoSpacing" style="margin: 0cm 0cm 0pt;"><span style="font-family: &quot;Times New Roman&quot;, &quot;serif&quot;; font-size: 12pt;">We can see that almost both lines red and blue are almost over-plotted in this case.</span><br /><br /><div class="separator" style="clear: both; text-align: center;"><a href="http://3.bp.blogspot.com/-HlUa31si-6g/T7KWC3mUHGI/AAAAAAAAAyg/_tofWY8uXKY/s1600/Monitor_003.JPG" imageanchor="1" style="margin-left: 1em; margin-right: 1em;" ref="nofollow" target="_blank"><img border="0" height="470" kba="true" src="http://3.bp.blogspot.com/-HlUa31si-6g/T7KWC3mUHGI/AAAAAAAAAyg/_tofWY8uXKY/s640/Monitor_003.JPG" width="640" /></a></div></div><div class="blogger-post-footer"><img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/2424328492215531658-7804051814544471253?l=nir-quimiometria.blogspot.com' alt='' /></div>
<p class="syndicated-attribution"><div style="border: 1px solid; background: none repeat scroll 0 0 #EDEDED; margin: 1px; font-size: 13px;">
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